Collagen fractions in lathyritic rats
The effect of β-aminopropionitrile (“Lathyrism”) on collagen was studied. Albino rats were fed with a diet containing 73 per cent sweet peas, and the bone changes resulting were ascertained by x-ray studies. The collagen fractions were prepared from skin and bone by extraction with disodium phosphat...
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| Veröffentlicht in: | Biochemical pharmacology 1960-06, Vol.3 (3), p.181-183 |
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| container_title | Biochemical pharmacology |
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| creator | Mikkonen, L. Tuominen, T. Kulonen, E. |
| description | The effect of β-aminopropionitrile (“Lathyrism”) on collagen was studied. Albino rats were fed with a diet containing 73 per cent sweet peas, and the bone changes resulting were ascertained by x-ray studies. The collagen fractions were prepared from skin and bone by extraction with disodium phosphate solution, acid citrate solution, and by gelatinization.
The alkali-soluble collagen was 5 times greater in cases of lathyrism. The solubility of non-collagenous proteins was also increased. The total collagen content was not altered. |
| doi_str_mv | 10.1016/0006-2952(60)90105-2 |
| format | Article |
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The alkali-soluble collagen was 5 times greater in cases of lathyrism. The solubility of non-collagenous proteins was also increased. The total collagen content was not altered.</description><subject>Animals</subject><subject>Collagen - chemistry</subject><subject>Cyanides - pharmacology</subject><subject>Lathyrism</subject><subject>Old Medline</subject><subject>Rats</subject><issn>0006-2952</issn><issn>1873-2968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1960</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LAzEQxYMotla_gcheFD2sTpJNNrkUpPgPCl70HNJkViPb3ZpshX57d23Rm6dhht-bmfcIOaVwTYHKGwCQOdOCXUq40kBB5GyPjKkqeT-Wap-Mf5EROUrpY2iVpIdkRHlZgmB6TM5nbV3bN2yyKlrXhbZJWWiy2nbvmxi64LJou3RMDipbJzzZ1Ql5vb97mT3m8-eHp9ntPHdcQpdz7rgHC4XS4FCCYt6h5p4BFcxpdLwqQFRYgWeWawaF8GphrSx8KYWgfEIutntXsf1cY-rMMiSH_YcNtutkFBO6pBp6sNiCLrYpRazMKoaljRtDwQzxmMGsGbwbCeYnHsN62dlu_3qxRP8n2uXRA9MtgL3Lr4DRJBewcehDRNcZ34b_L3wDDTByHw</recordid><startdate>196006</startdate><enddate>196006</enddate><creator>Mikkonen, L.</creator><creator>Tuominen, T.</creator><creator>Kulonen, E.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196006</creationdate><title>Collagen fractions in lathyritic rats</title><author>Mikkonen, L. ; Tuominen, T. ; Kulonen, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-33c3d0a04890ce6082dce93d20152c9ec3f405fef0d2a392045d8baa64d765513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1960</creationdate><topic>Animals</topic><topic>Collagen - chemistry</topic><topic>Cyanides - pharmacology</topic><topic>Lathyrism</topic><topic>Old Medline</topic><topic>Rats</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mikkonen, L.</creatorcontrib><creatorcontrib>Tuominen, T.</creatorcontrib><creatorcontrib>Kulonen, E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biochemical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mikkonen, L.</au><au>Tuominen, T.</au><au>Kulonen, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Collagen fractions in lathyritic rats</atitle><jtitle>Biochemical pharmacology</jtitle><addtitle>Biochem Pharmacol</addtitle><date>1960-06</date><risdate>1960</risdate><volume>3</volume><issue>3</issue><spage>181</spage><epage>183</epage><pages>181-183</pages><issn>0006-2952</issn><eissn>1873-2968</eissn><abstract>The effect of β-aminopropionitrile (“Lathyrism”) on collagen was studied. Albino rats were fed with a diet containing 73 per cent sweet peas, and the bone changes resulting were ascertained by x-ray studies. The collagen fractions were prepared from skin and bone by extraction with disodium phosphate solution, acid citrate solution, and by gelatinization.
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| fulltext | fulltext |
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| ispartof | Biochemical pharmacology, 1960-06, Vol.3 (3), p.181-183 |
| issn | 0006-2952 1873-2968 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Collagen - chemistry Cyanides - pharmacology Lathyrism Old Medline Rats |
| title | Collagen fractions in lathyritic rats |
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