Electrophoretic polymorphism of adenylate kinase in human jejunum

Paired specimens of human red blood cells and jejunal mucosal biopsy specimens have been examined for two enzyme polymorphisms by starch gel electrophoresis. The 24 jejunal specimens showed identical adenylate kinase phenotypes to the red cell samples (21 type AK 1-1 and 3 type AK 2-1). This informa...

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Veröffentlicht in:	Clinica chimica acta 1974-10, Vol.56 (1), p.91-95
Hauptverfasser:	Eze, L.C., Evans, D.A.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Adenosine Monophosphate Duodenal Ulcer - enzymology Electrophoresis, Starch Gel Erythrocytes - enzymology Humans Intestinal Mucosa - enzymology Isoenzymes - metabolism Jejunum - enzymology Phenotype Phosphotransferases - blood Phosphotransferases - metabolism Polymorphism, Genetic
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Zusammenfassung:	Paired specimens of human red blood cells and jejunal mucosal biopsy specimens have been examined for two enzyme polymorphisms by starch gel electrophoresis. The 24 jejunal specimens showed identical adenylate kinase phenotypes to the red cell samples (21 type AK 1-1 and 3 type AK 2-1). This information could be used for surveys of patients with gastrointestinal disorders. Jejunal samples from 12 patients of various acid phosphatase phenotypes all showed identical isoenzyme patterns on starch gel electrophoresis. Consequently, the red cell acid phosphatase polymorphism has not been demonstrated in the jejunum.
ISSN:	0009-8981 1873-3492
DOI:	10.1016/0009-8981(74)90196-X