The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay

It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of...

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Veröffentlicht in:The Journal of immunology (1950) 1974-12, Vol.113 (6), p.1952-1957
Hauptverfasser: Day, Eugene D, Wexler, Marjorie A
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container_end_page 1957
container_issue 6
container_start_page 1952
container_title The Journal of immunology (1950)
container_volume 113
creator Day, Eugene D
Wexler, Marjorie A
description It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of antibody in microliter quantities of serum without untoward loss of statistical precision.
doi_str_mv 10.4049/jimmunol.113.6.1952
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identifier ISSN: 0022-1767
ispartof The Journal of immunology (1950), 1974-12, Vol.113 (6), p.1952-1957
issn 0022-1767
1550-6606
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source MEDLINE; Alma/SFX Local Collection
subjects Animals
Antibody Formation
Encephalomyelitis, Autoimmune, Experimental - immunology
Freund's Adjuvant
Immune Sera
Immunization
Immunization, Secondary
Iodine Radioisotopes
Isotope Labeling
Male
Myelin Basic Protein
Myelin Sheath - immunology
Radioimmunoassay
Rats
Rats, Inbred F344
Rats, Inbred Lew
Sodium Tetradecyl Sulfate
title The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay
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