The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay
It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of...
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Veröffentlicht in: | The Journal of immunology (1950) 1974-12, Vol.113 (6), p.1952-1957 |
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container_end_page | 1957 |
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container_issue | 6 |
container_start_page | 1952 |
container_title | The Journal of immunology (1950) |
container_volume | 113 |
creator | Day, Eugene D Wexler, Marjorie A |
description | It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of antibody in microliter quantities of serum without untoward loss of statistical precision. |
doi_str_mv | 10.4049/jimmunol.113.6.1952 |
format | Article |
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Wexler, Marjorie A</creator><creatorcontrib>Day, Eugene D ; Wexler, Marjorie A</creatorcontrib><description>It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of antibody in microliter quantities of serum without untoward loss of statistical precision.</description><identifier>ISSN: 0022-1767</identifier><identifier>EISSN: 1550-6606</identifier><identifier>DOI: 10.4049/jimmunol.113.6.1952</identifier><identifier>PMID: 4139201</identifier><language>eng</language><publisher>United States: Am Assoc Immnol</publisher><subject>Animals ; Antibody Formation ; Encephalomyelitis, Autoimmune, Experimental - immunology ; Freund's Adjuvant ; Immune Sera ; Immunization ; Immunization, Secondary ; Iodine Radioisotopes ; Isotope Labeling ; Male ; Myelin Basic Protein ; Myelin Sheath - immunology ; Radioimmunoassay ; Rats ; Rats, Inbred F344 ; Rats, Inbred Lew ; Sodium Tetradecyl Sulfate</subject><ispartof>The Journal of immunology (1950), 1974-12, Vol.113 (6), p.1952-1957</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-3947774b3cd0ff3f0e3436ab32db91c0e55405afb9e724b6e5c4d9abd8f035293</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4139201$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Day, Eugene D</creatorcontrib><creatorcontrib>Wexler, Marjorie A</creatorcontrib><title>The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay</title><title>The Journal of immunology (1950)</title><addtitle>J Immunol</addtitle><description>It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of antibody in microliter quantities of serum without untoward loss of statistical precision.</description><subject>Animals</subject><subject>Antibody Formation</subject><subject>Encephalomyelitis, Autoimmune, Experimental - immunology</subject><subject>Freund's Adjuvant</subject><subject>Immune Sera</subject><subject>Immunization</subject><subject>Immunization, Secondary</subject><subject>Iodine Radioisotopes</subject><subject>Isotope Labeling</subject><subject>Male</subject><subject>Myelin Basic Protein</subject><subject>Myelin Sheath - immunology</subject><subject>Radioimmunoassay</subject><subject>Rats</subject><subject>Rats, Inbred F344</subject><subject>Rats, Inbred Lew</subject><subject>Sodium Tetradecyl Sulfate</subject><issn>0022-1767</issn><issn>1550-6606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkN-L1DAQx4Mo53r6F4iQJ33qmt_dPp7HrQp7KHfnc0iaic2RNmvTUvrqX26OXUUYGGbmO19mPgi9pWQriGg-Poa-n4cUt5TyrdrSRrJnaEOlJJVSRD1HG0IYq2it6pfoVc6PhBBFmLhAF4LyhhG6Qb8fOsBXwxRsciu-g3xMQwY8JXy7QgwD_mRyaPH3MU1QqhIHWELGZnB4H3LbwYjvzFQaGe9TjGkBh-2KDb5PLsw9vp-jNxPgW5i65HDyRe5COp1ucjbra_TCm5jhzTlfoh_7m4frL9Xh2-ev11eHquWcTRVvRF3XwvLWEe-5J8AFV8Zy5mxDWwJSCiKNtw3UTFgFshWuMdbtPOGSNfwSvT_5Hsf0a4Y86b48ADGaAdKc9Y5JJRTZFSE_Cdsx5TyC18cx9GZcNSX6ibz-S14X8lrpJ_Jl693ZfrY9uH87Z9Rl_uE078LPbgkj6NybGIua6mVZ_nP6AzbvkCI</recordid><startdate>197412</startdate><enddate>197412</enddate><creator>Day, Eugene D</creator><creator>Wexler, Marjorie A</creator><general>Am Assoc Immnol</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197412</creationdate><title>The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay</title><author>Day, Eugene D ; Wexler, Marjorie A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-3947774b3cd0ff3f0e3436ab32db91c0e55405afb9e724b6e5c4d9abd8f035293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Animals</topic><topic>Antibody Formation</topic><topic>Encephalomyelitis, Autoimmune, Experimental - immunology</topic><topic>Freund's Adjuvant</topic><topic>Immune Sera</topic><topic>Immunization</topic><topic>Immunization, Secondary</topic><topic>Iodine Radioisotopes</topic><topic>Isotope Labeling</topic><topic>Male</topic><topic>Myelin Basic Protein</topic><topic>Myelin Sheath - immunology</topic><topic>Radioimmunoassay</topic><topic>Rats</topic><topic>Rats, Inbred F344</topic><topic>Rats, Inbred Lew</topic><topic>Sodium Tetradecyl Sulfate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Day, Eugene D</creatorcontrib><creatorcontrib>Wexler, Marjorie A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of immunology (1950)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Day, Eugene D</au><au>Wexler, Marjorie A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay</atitle><jtitle>The Journal of immunology (1950)</jtitle><addtitle>J Immunol</addtitle><date>1974-12</date><risdate>1974</risdate><volume>113</volume><issue>6</issue><spage>1952</spage><epage>1957</epage><pages>1952-1957</pages><issn>0022-1767</issn><eissn>1550-6606</eissn><abstract>It was found that the sodium sulfate method of radioimmunoassay of 125I-labeled myelin basic protein could be used in the measurement and linear regression analysis of myelin-basic protein-binding activity in Lewis and Fischer rats, and could be adapted to the day-to-day single point measurements of antibody in microliter quantities of serum without untoward loss of statistical precision.</abstract><cop>United States</cop><pub>Am Assoc Immnol</pub><pmid>4139201</pmid><doi>10.4049/jimmunol.113.6.1952</doi><tpages>6</tpages></addata></record> |
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ispartof | The Journal of immunology (1950), 1974-12, Vol.113 (6), p.1952-1957 |
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language | eng |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Animals Antibody Formation Encephalomyelitis, Autoimmune, Experimental - immunology Freund's Adjuvant Immune Sera Immunization Immunization, Secondary Iodine Radioisotopes Isotope Labeling Male Myelin Basic Protein Myelin Sheath - immunology Radioimmunoassay Rats Rats, Inbred F344 Rats, Inbred Lew Sodium Tetradecyl Sulfate |
title | The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay |
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