A Controlled Trial of Iproniazid in the Treatment of Endogenous Depression

In conducting drug trials nowadays one is aware of at least some of the difficulties that have to be faced and the possible traps lying ahead. It is probably true to say that perfection is unattainable in trials of this nature because of the unpredictability of the human material concerned—both the tested and the observers sharing this common fallibility. It is necessary to attempt so to arrange the experiment that the magnitude of the errors is kept to a minimum and the results remain unobscured.