Pharmacokinetics of lithium and its regional distribution in rat brain

The experimental evidence indicates that lithium is distributed unevenly in the brain. Among areas studied, the highest concentrations of lithium were found in the basal ganglia and the pituitary, and the lowest in spinal cord, pons and medulla.

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 1974-08, Vol.27 (3), p.324-329
Hauptverfasser:	Ebadi, Manuchair S., Simmons, Vickie J., Hendrickson, Merrill J., Lacy, Priti S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basal ganglia Biological Transport Brain - metabolism Brain areas Brain Chemistry Injections, Intravenous Lithium Lithium - administration & dosage Lithium - analysis Lithium - blood Lithium - metabolism Lithium toxicity Male Rats Spectrophotometry, Atomic Transport ATPase
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Beschreibung
Zusammenfassung:	The experimental evidence indicates that lithium is distributed unevenly in the brain. Among areas studied, the highest concentrations of lithium were found in the basal ganglia and the pituitary, and the lowest in spinal cord, pons and medulla.
ISSN:	0014-2999 1879-0712
DOI:	10.1016/0014-2999(74)90007-7