Identification of Breast Cancer Patients With High Risk of Early Recurrence After Radical Mastectomy. I. Description of Study

A cooperative investigation was undertaken to assess the prognostic significance of combinations of various clinical, pathologic, and urinary steroid variables in patients with breast cancer treated by radical mastectomy. The protocol was detailed; data were collected for 19 selected variables from 98 patients in whom the 2-year recurrence or nonrecurrence status was known. Lymph node involvement and blood vessel invasion had prognostic significance when considered as single variables. Indices using multiple variables are under development.