PHARMACOLOGICAL ACTION OF GABA ON THE BRAIN STEM ACTIVITIES

PHARMACOLOGICAL ACTION OF GABA ON THE BRAIN STEM ACTIVITIES

Systemic GABA caused a fall in blood pressure, some changes in respiration and facilitation on the flexor reflex. Further, it could facilitate knee jerk under some suppressive condition (for example, chlorpromazine-poisoning). The site of action of GABA on the spinal reflex was also in the brain ste...

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Veröffentlicht in:Japanese journal of physiology 1959, Vol.9(4), pp.468-472
Hauptverfasser: TAKAHASHI, HIDEHIKO, YAMAZAKI, TOSHIHITO, MATSUZAKI, HIROMICHI, MURAI, TAKAYOSHI
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acids - pharmacology
Brain Stem - physiology
gamma-Aminobutyric Acid
Nervous System Physiological Phenomena
Old Medline
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Zusammenfassung:Systemic GABA caused a fall in blood pressure, some changes in respiration and facilitation on the flexor reflex. Further, it could facilitate knee jerk under some suppressive condition (for example, chlorpromazine-poisoning). The site of action of GABA on the spinal reflex was also in the brain stem. The authors assume that systemic GABA has a specific affinity to the re ticular system and it is not a mere inhibitory substance in the mammals.
ISSN:0021-521X
1881-1396
DOI:10.2170/jjphysiol.9.468