PURIFICATION OF AN IMMUNOSUPPRESSIVE PRINCIPLE DERIVED FROM EHRLICH CARCINOMA CELLS

Immunosuppressive principles were purified from Ehrlich ascites tumor cells. One of the principles, D3-1 with molecular weight of 76, 000, showed a single protein band on polyacrylamide gel electrophoresis. Immunosuppression was assayed by counting 19S antibody plaque-forming cells against sheep red...

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Veröffentlicht in:	GANN Japanese Journal of Cancer Research 1974/06/30, Vol.65(3), pp.269-271
Hauptverfasser:	MOTOKI, Hiroaki, KAMO, Isao, KIKUCHI, Mikio, ONO, Yasushi, ISHIDA, Nakao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Ehrlich Tumor - metabolism Cellular component Chromatography Chromatography, Gel Ehrlich ascites tumor Electrophoresis Female Immunosuppression Immunosuppressive Agents - isolation & purification Mice Molecular Weight Mouse
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Zusammenfassung:	Immunosuppressive principles were purified from Ehrlich ascites tumor cells. One of the principles, D3-1 with molecular weight of 76, 000, showed a single protein band on polyacrylamide gel electrophoresis. Immunosuppression was assayed by counting 19S antibody plaque-forming cells against sheep red blood cells in mouse spleen.
ISSN:	0016-450X
DOI:	10.20772/cancersci1959.65.3_269