Micellar Properties of Drugs: Determination of Molecular Weight, Size, and Molecular Interactions of Drug Micelles Using the Analytical Ultracentrifuge

This article illustrates the usefulness of the analytical ultracentrifuge in investigating micellar properties of drugs. Also discussed are some examples of micelle forms of drugs and the working hypothesis that the same binding forces that hold together the aggregate found at high concentrations may be responsible for the binding of monomer (at physiological concentrations) to biological structures.