Effects of glucagon on cholesterol and triglyceride deposition in tissues

In rats on a high lipid diet a study was done on the effect of glucagon injections on cholesterol and triglyceride levels in plasma, liver, kidney, heart muscle, and aorta. There was little effect on the concentration of triglycerides and cholesterol in the liver or in the diaphragm. However, the le...

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Veröffentlicht in:	Biochemical medicine 1974-06, Vol.10 (2), p.122-125
Hauptverfasser:	Rothfeld, Benjamin, Margolis, Simeon, Varady, Alexander, Karmen, Arthur
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - metabolism Cholesterol - blood Cholesterol - metabolism Depression, Chemical Diaphragm - metabolism Dietary Fats Glucagon - pharmacology Kidney - metabolism Lipids Liver - metabolism Male Rats Triglycerides - blood Triglycerides - metabolism
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Beschreibung
Zusammenfassung:	In rats on a high lipid diet a study was done on the effect of glucagon injections on cholesterol and triglyceride levels in plasma, liver, kidney, heart muscle, and aorta. There was little effect on the concentration of triglycerides and cholesterol in the liver or in the diaphragm. However, the level of these lipids was significantly decreased in the kidney, aorta, and serum. Possible explanations for the findings are offered.
ISSN:	0006-2944 1557-7996
DOI:	10.1016/0006-2944(74)90014-3