Vaginal fluid subsequent to panhysterectomy

1.1. Subsequent to panhysterectomy 26 individuals yielded a total of 47.91 Gm. of fluid during 639 hours, an average of 1.8 Gm. per subject per 24 hours. (Range 1.2 to 2.14 Gm. per 24 hours.) (Table I.)2.2. Ten patients, following panhysterectomy and oophorectomy and without hormone therapy, yielded an average of 1.54 Gm. per day of vaginal fluid. (Range 1.2 to 1.68 Gm. per 24 hours.)3.3. Sixteen patients with intact ovaries with or without hormone therapy yielded an average of 1.93 Gm. per day of vaginal fluid. (Range 1.44 to 2.14 Gm. per 24 hours.)4.4. It is suggested that the vaginal moisture, following panhysterectomy, is largely derived from a transepithelially migrating fluid comparable in dynamics to the transepidermal insensible water loss through the skin.5.5. The daily average amount of recoverable fluid from the vagina following panhysterectomy (1.8 Gm.) approximates a computed figure obtained from the calculated transepithelial water loss from an area approximating the vaginal surface (2.1 Gm.).