Studies in calcium metabolism. I. The calciuretic effect of dietary protein

Data are presented from several studies concerning the effect of varying protein intake on urinary calcium excretion, A markedly positive correlation was found between protein ingestion and calciuria. Although the response was not linear, varying protein intake from 0 g to 90 g N per day results in approximately an 800% increase in calcium excretion, irrespective of calcium intake. This effect of protein occurred in all our studies of individuals, and was also observed with purel-amino acid mixtures.