Histological and biochemical studies on the retina of a new strain of dystrophic rat

Histological and biochemical studies on the retina of a new strain of dystrophic rat

A strain of pigmented dystrophic rats has been bred from albino dystrophic rats and pigmented sighted rats. The progress of retinal degeneration has been assessed histologically and biochemically (by estimation of RNA and DNA levels). The onset and progression of the lesion in the pigmented dystroph...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental eye research 1974-02, Vol.18 (2), p.119-133
Hauptverfasser: Yates, Celia M., Dewar, A.J., Wilson, Helen, Winterburn, Ann K., Reading, H.W.
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Animals
Biometry
Brain Chemistry
DNA - analysis
Female
Light
Male
Photoreceptor Cells
Proteins - analysis
Rats
Rats, Inbred Strains
Retina - analysis
Retina - pathology
Retinal Degeneration - etiology
Retinal Degeneration - pathology
Retinitis Pigmentosa - pathology
RNA - analysis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A strain of pigmented dystrophic rats has been bred from albino dystrophic rats and pigmented sighted rats. The progress of retinal degeneration has been assessed histologically and biochemically (by estimation of RNA and DNA levels). The onset and progression of the lesion in the pigmented dystrophic rats were delayed by about one week compared with the albino dystrophic rats. It is concluded that the presence of pigment in the eye retards the degenerative process.
ISSN:0014-4835
1096-0007
DOI:10.1016/0014-4835(74)90098-0