Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV

Rous sarcoma virus (RSV) transforms different species of mammalian cells. The RSV genome is usually not fully expressed in such cells and the virogenic type of virus-cell interaction is obtained 1,2 . One exception was, however, noted by Svoboda and Klement 3 in the case of some hamster tumours indu...

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Veröffentlicht in:Nature (London) 1974-04, Vol.248 (5448), p.503-505
Hauptverfasser: SVOBODA, JAN, DONNER, LUDVÍK, MACH, OTAKAR
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DONNER, LUDVÍK
MACH, OTAKAR
description Rous sarcoma virus (RSV) transforms different species of mammalian cells. The RSV genome is usually not fully expressed in such cells and the virogenic type of virus-cell interaction is obtained 1,2 . One exception was, however, noted by Svoboda and Klement 3 in the case of some hamster tumours induced by Prague strain of RSV (PR RSV) which were found to produce traces (about 1 ID 50 per 2.5 g tumour tissue) of infectious RSV.
doi_str_mv 10.1038/248503a0
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subjects Animals
Antigens, Viral - analysis
Avian Sarcoma Viruses - immunology
Avian Sarcoma Viruses - metabolism
Cell Line
Cell Transformation, Neoplastic
Fluorescent Antibody Technique
Humanities and Social Sciences
Karyotyping
letter
Marsupialia
Microscopy, Electron
multidisciplinary
Science
Science (multidisciplinary)
Thymidine - metabolism
Tritium
Uridine - metabolism
Virus Replication
title Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV
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