Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV

Rous sarcoma virus (RSV) transforms different species of mammalian cells. The RSV genome is usually not fully expressed in such cells and the virogenic type of virus-cell interaction is obtained 1,2 . One exception was, however, noted by Svoboda and Klement 3 in the case of some hamster tumours indu...

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Veröffentlicht in:	Nature (London) 1974-04, Vol.248 (5448), p.503-505
Hauptverfasser:	SVOBODA, JAN, DONNER, LUDVÍK, MACH, OTAKAR
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Viral - analysis Avian Sarcoma Viruses - immunology Avian Sarcoma Viruses - metabolism Cell Line Cell Transformation, Neoplastic Fluorescent Antibody Technique Humanities and Social Sciences Karyotyping letter Marsupialia Microscopy, Electron multidisciplinary Science Science (multidisciplinary) Thymidine - metabolism Tritium Uridine - metabolism Virus Replication
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Beschreibung
Zusammenfassung:	Rous sarcoma virus (RSV) transforms different species of mammalian cells. The RSV genome is usually not fully expressed in such cells and the virogenic type of virus-cell interaction is obtained 1,2 . One exception was, however, noted by Svoboda and Klement 3 in the case of some hamster tumours induced by Prague strain of RSV (PR RSV) which were found to produce traces (about 1 ID 50 per 2.5 g tumour tissue) of infectious RSV.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/248503a0