Preparation and isolation of immunologically active glycopeptides from carcinoembryonic antigen (CEA)

In order to determine the structure of the tumor‐specific immunodominant group of the carcinoembryonic antigen (CEA) of human gastro‐intestinal tumors, immunologically active fragments from this glycoprotein were prepared by partial enzymatic hydrolysis using the proteolytic enzyme nagase. The fragm...

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Veröffentlicht in:	International journal of cancer 1974-02, Vol.13 (2), p.151-163
Hauptverfasser:	Banjo, C., Gold, P., Gehrke, C. W., Freedman, S. O., Krupey, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - analysis Animals Antigens Autoanalysis Carcinoembryonic Antigen - analysis Chromatography, DEAE-Cellulose Chromatography, Gas Chromatography, Gel Chromatography, Ion Exchange Colonic Neoplasms - immunology Electrophoresis, Paper Glucose Oxidase - pharmacology Glycopeptides - analysis Immune Sera Iodine Radioisotopes Liver Neoplasms - immunology Methods Molecular Weight Monosaccharides - analysis Neoplasm Metastasis Neuraminidase - pharmacology Radioimmunoassay Subtilisins - pharmacology Tritium
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