Highly Fluorescent Silica-Coated Bismuth-Doped Aluminosilicate Nanoparticles for Near-Infrared Bioimaging

Highly Fluorescent Silica-Coated Bismuth-Doped Aluminosilicate Nanoparticles for Near-Infrared Bioimaging

The combined advantages of bismuth and aluminosilicates lead to a new type of nanosized biolabel. The near‐infrared (NIR)‐emitting silica‐coated bismuth‐doped aluminosilicate nanoparticles are simple to prepare and exhibit a broad excitation band in the first biological window, efficient long‐lived...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2011-01, Vol.7 (2), p.199-203
Hauptverfasser: Sun, Hong-Tao, Yang, Junjie, Fujii, Minoru, Sakka, Yoshio, Zhu, Yufang, Asahara, Takayuki, Shirahata, Naoto, Ii, Masaaki, Bai, Zhenhua, Li, Ji-Guang, Gao, Hong
Format: Artikel
Sprache:eng
Schlagworte:
aluminosilicates
Aluminum Silicates - chemistry
bioimaging
biomaterials
bismuth
Bismuth - chemistry
Diagnostic Imaging - instrumentation
Diagnostic Imaging - methods
Nanoparticles - chemistry
Nanotechnology
photoluminescence
Silicon Dioxide - chemistry
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Zusammenfassung:The combined advantages of bismuth and aluminosilicates lead to a new type of nanosized biolabel. The near‐infrared (NIR)‐emitting silica‐coated bismuth‐doped aluminosilicate nanoparticles are simple to prepare and exhibit a broad excitation band in the first biological window, efficient long‐lived photoluminescence (PL) covering the second window, high photostability, low cytotoxicity, and easy penetration into living tissues. In vivo PL bioimaging and decay are tested in living mice.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201001011