Effect of Adrenalectomy and Hydrocortisone on Lymph Glucose in Rats.

Summary 1. It is confirmed that in the fasted state lymph glucose is in equilibrium with blood plasma glucose, probably at the capillary level. 2. Less than 0.3% of absorbed glucose appears in the lymphatic stream. 3. The greater quantity of glucose which enters the blood capillaries in normal fasted rats is explained on the basis of difference in rates of blood flow and lymph formation rather than endothelial selectivity 4. Plasma and lymph glucose values are low in adrenalectomized rats but are returned toward normal by pretreatment with hydrocortisone. 5. Lymph flow in hydrocortisone pretreated rats is increased by 100% after gavage of glucose solution but not after water gavage.