Estimating chromatographic enantioselectivity (α) from gradient enantioselective chromatography data

Calculation of chromatographic enantioselectivity (α) is critically important in enantioselective chromatographic method development studies. The fact that α can only be calculated from isocratic elution conditions, whereas gradient elution conditions are predominantly used in method development scr...

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Veröffentlicht in:	Chirality (New York, N.Y.) N.Y.), 2011-02, Vol.23 (2), p.128-132
Hauptverfasser:	Gong, Xiaoyi, Craven, Tim, Schafer, Wes, Pirzada, Zainab, Biba, Mirlinda, Welch, Christopher J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms automated chromatography Cellulose - analogs & derivatives Chemistry Techniques, Analytical - methods Chromatography, Liquid - methods Chromatography, Supercritical Fluid - methods enantioselectivity gradient elution method development Small Molecule Libraries - chemistry Stereoisomerism
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