Bioconversion of hydrocortisone by cyanobacterium Fischerella ambigua PTCC 1635

Bioconversion of hydrocortisone by cyanobacterium Fischerella ambigua PTCC 1635

The bioconversion of hydrocortisone by a locally isolated strain of cyanobacterium Fischerella ambigua PTCC 1635 was investigated. Fischerella ambigua had not been previously examined for this potential. The fermentation led to production of 11β,17α, 20β, 21-tetrahydroxypregn-4-en-3-one and 11β-hydr...

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Veröffentlicht in:World journal of microbiology & biotechnology 2005-10, Vol.21 (6-7), p.811-814
Hauptverfasser: MOJTABA TABATABAEI YAZDI, GHASEMI, Younes, GHASEMIAN, Abdollah, SHOKRAVI, Shadman, NIKNAHAD, Hossein, AMINI, Mohsen, DEHSHAHRI, Ali, MOHAMMAD ALI FARAMARZI
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Bioconversion
Biological and medical sciences
Biotechnology
Chromatography
Cyanophyta
Fermentation
Fischerella ambigua
Fundamental and applied biological sciences. Psychology
Hydrocortisone
Metabolites
Microbiology
Strain
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Zusammenfassung:The bioconversion of hydrocortisone by a locally isolated strain of cyanobacterium Fischerella ambigua PTCC 1635 was investigated. Fischerella ambigua had not been previously examined for this potential. The fermentation led to production of 11β,17α, 20β, 21-tetrahydroxypregn-4-en-3-one and 11β-hydroxyandrost-4-en-3,17-dione. The metabolites were isolated and purified by chromatographic methods and identified using instrumental analyses.[PUBLICATION ABSTRACT]
ISSN:0959-3993
1573-0972
DOI:10.1007/s11274-004-2238-9