Genetic Differences in Hemoglobin as Markers for Bone Marrow Transplantation in Mice

Genetic Differences in Hemoglobin as Markers for Bone Marrow Transplantation in Mice

Summary Both hemoglobin type and red cell serotype seem to be autonomously controlled by the genotype of the nucleated cell from which the erythrocyte is derived. Thus, genetic differences in hemoglobin can be used as markers for bone marrow transplantation in irradiated mice. Hemoglobin typing may...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1958-12, Vol.99 (3), p.692-694
Hauptverfasser: Popp, Raymond A., Cosgrove, G. E., Owen, R. D.
Format: Artikel
Sprache:eng
Schlagworte:
ANIMAL CELLS
Animals
BIOLOGY AND MEDICINE
BLOOD FORMATION
BONE MARROW
Bone Marrow Transplantation
CHROMOSOMES
ERYTHROCYTES
GENES
GENETICS
HEMOGLOBIN
Hemoglobin, Sickle
Hemoglobins
MICE
Old Medline
TRANSPLANTS
VARIATIONS
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Zusammenfassung:Summary Both hemoglobin type and red cell serotype seem to be autonomously controlled by the genotype of the nucleated cell from which the erythrocyte is derived. Thus, genetic differences in hemoglobin can be used as markers for bone marrow transplantation in irradiated mice. Hemoglobin typing may be particularly useful where the H-2 markers cannot be used.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-99-24465