NORMAL VALUES OF THE SERUM PROTEIN FRACTIONS IN CYNOMOLGUS MONKEYS USED AS EXPERIMENTAL ANIMALS

Serum protein fraction values were determined by electrophoretic separation with apparently healthy 24 laboratory-bred cynomolgus monkeys and 40 female laboratory-conditioned ones of wild origin. We found that β-globulin was always separated into two fractions. This finding seems to reflect an intrinsic nature of β-globulin of this species. Statistically significant differences were found between young (1-2 years old) and matured (4-6 years old) laboratory-bred monkeys with regard to the total protein content and the α2-globulin value. No statistically significant difference was noted between males and females of laboratory-bred monkeys. There was clear difference between the laboratory-bred and laboratory-conditioned monkeys in the levels of serum protein fractions; the γ-globulin value being lower and the albumin value higher in the former group than in the latter. A probable ellipse was drawn on the basis of the combined data of the albumin and γ-globulin values. It would serve as a graphic criterion for conditioning wild imported monkeys. Its applicability was studied with groups of wildimported monkeys at various stages of conditioning after their arrival.