Effects of treatment of peripheral pain generators in fibromyalgia patients

Research highlights ► Myofascial trigger points and painful joints are very frequent in fibromyalgia (FS). ► FS symptoms improve after active but not placebo local trigger/joint therapy. ► Nociceptive input from the somatic periphery enhances central sensitization in FS. ► Identification and treatme...

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Veröffentlicht in:	European journal of pain 2011-01, Vol.15 (1), p.61-69
Hauptverfasser:	Affaitati, Giannapia, Costantini, Raffaele, Fabrizio, Alessandra, Lapenna, Domenico, Tafuri, Emmanuele, Giamberardino, Maria Adele
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anesthesia & Perioperative Care Anesthetics, Local - administration & dosage Anesthetics, Local - therapeutic use Arthralgia - drug therapy Arthralgia - physiopathology Comorbidity Female Fibromyalgia Fibromyalgia - drug therapy Fibromyalgia - physiopathology Follow-Up Studies Humans Joint Local treatment Middle Aged Muscle, Skeletal - drug effects Muscle, Skeletal - physiopathology Myofascial Pain Syndromes - drug therapy Myofascial Pain Syndromes - physiopathology Pain Measurement - methods Pain Medicine Pain Threshold - drug effects Peripheral pain generators Severity of Illness Index Time Factors Treatment Outcome Trigger point Young Adult
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Beschreibung
Zusammenfassung:	Research highlights ► Myofascial trigger points and painful joints are very frequent in fibromyalgia (FS). ► FS symptoms improve after active but not placebo local trigger/joint therapy. ► Nociceptive input from the somatic periphery enhances central sensitization in FS. ► Identification and treatment of peripheral pain sources are recommended in FS.
ISSN:	1090-3801 1532-2149
DOI:	10.1016/j.ejpain.2010.09.002