Deiodination of Thyroxine and Other Iodinated Compounds During Desalting by Electrodialysis.
Conclusions 1) Use of electrolytic desalter to remove inorganic ions from solution, results in removal of iodine from aromatic linkage, including thyroxine, triiodothyronine, diiodotyrosine and several of the fatty acid side-chain analogues of thyroxine. 2) This prevents use of apparatus for prepara...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1958-08, Vol.98 (4), p.780-782 |
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| container_end_page | 782 |
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| container_issue | 4 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 98 |
| creator | Etling, Nicole Barker, S. B. |
| description | Conclusions
1) Use of electrolytic desalter to remove inorganic ions from solution, results in removal of iodine from aromatic linkage, including thyroxine, triiodothyronine, diiodotyrosine and several of the fatty acid side-chain analogues of thyroxine. 2) This prevents use of apparatus for preparation of salt-free solutions in thyroid studies. The procedure might be useful in preparation of various dehalogenated derivatives where the parent compounds are readily available. |
| doi_str_mv | 10.3181/00379727-98-24184 |
| format | Article |
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1) Use of electrolytic desalter to remove inorganic ions from solution, results in removal of iodine from aromatic linkage, including thyroxine, triiodothyronine, diiodotyrosine and several of the fatty acid side-chain analogues of thyroxine. 2) This prevents use of apparatus for preparation of salt-free solutions in thyroid studies. The procedure might be useful in preparation of various dehalogenated derivatives where the parent compounds are readily available.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-98-24184</identifier><identifier>PMID: 13591342</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Halogenation ; Immunologic Tests ; Old Medline ; Thyroxine - analogs & derivatives ; Triiodothyronine - analogs & derivatives</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1958-08, Vol.98 (4), p.780-782</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13591342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Etling, Nicole</creatorcontrib><creatorcontrib>Barker, S. B.</creatorcontrib><title>Deiodination of Thyroxine and Other Iodinated Compounds During Desalting by Electrodialysis.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Conclusions
1) Use of electrolytic desalter to remove inorganic ions from solution, results in removal of iodine from aromatic linkage, including thyroxine, triiodothyronine, diiodotyrosine and several of the fatty acid side-chain analogues of thyroxine. 2) This prevents use of apparatus for preparation of salt-free solutions in thyroid studies. The procedure might be useful in preparation of various dehalogenated derivatives where the parent compounds are readily available.</description><subject>Halogenation</subject><subject>Immunologic Tests</subject><subject>Old Medline</subject><subject>Thyroxine - analogs & derivatives</subject><subject>Triiodothyronine - analogs & derivatives</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1958</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRbK3-AC-yJ2-p-5GP3aO0VQuFXupNWDbZSZuSZOtuAubfm5iKN08zMM_7wjwI3VMy51TQJ0J4IhOWBFIELKQivEBTGvEo4LGUl2g63IMBmKAb74-E0Chh8TWaUB5JykM2RR9LKKwpat0UtsY2x7tD5-xXUQPWtcHb5gAOr0cCDF7Y6mTb2ni8bF1R7_ESvC6bYUs7vCoha1wP67LzhZ_foqtclx7uznOG3l9Wu8VbsNm-rhfPmyBjkjRBLA0PudZEaxqSjBIQYUQpZyTNYiMh4sDyhOiUZAaMoEKGJM2NiFPCEp1nfIYex96Ts58t-EZVhc-gLHUNtvVKMMY47z-eITqCmbPeO8jVyRWVdp2iRA1K1a9SJYX6UdpnHs7lbVqB-UucHfbAfAS83oM62tbV_bP_NH4DsoF_og</recordid><startdate>195808</startdate><enddate>195808</enddate><creator>Etling, Nicole</creator><creator>Barker, S. B.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195808</creationdate><title>Deiodination of Thyroxine and Other Iodinated Compounds During Desalting by Electrodialysis.</title><author>Etling, Nicole ; Barker, S. B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c290t-69d343aa0aa140c10e84511320bc6d9e53e2f70ab0cded818940bfd86b027afc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1958</creationdate><topic>Halogenation</topic><topic>Immunologic Tests</topic><topic>Old Medline</topic><topic>Thyroxine - analogs & derivatives</topic><topic>Triiodothyronine - analogs & derivatives</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Etling, Nicole</creatorcontrib><creatorcontrib>Barker, S. B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Etling, Nicole</au><au>Barker, S. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deiodination of Thyroxine and Other Iodinated Compounds During Desalting by Electrodialysis.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1958-08</date><risdate>1958</risdate><volume>98</volume><issue>4</issue><spage>780</spage><epage>782</epage><pages>780-782</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Conclusions
1) Use of electrolytic desalter to remove inorganic ions from solution, results in removal of iodine from aromatic linkage, including thyroxine, triiodothyronine, diiodotyrosine and several of the fatty acid side-chain analogues of thyroxine. 2) This prevents use of apparatus for preparation of salt-free solutions in thyroid studies. The procedure might be useful in preparation of various dehalogenated derivatives where the parent compounds are readily available.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13591342</pmid><doi>10.3181/00379727-98-24184</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1958-08, Vol.98 (4), p.780-782 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82223391 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Halogenation Immunologic Tests Old Medline Thyroxine - analogs & derivatives Triiodothyronine - analogs & derivatives |
| title | Deiodination of Thyroxine and Other Iodinated Compounds During Desalting by Electrodialysis. |
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