Morphology of Transplantable Chorionic Tumors in Rats

Three lines of transplantable chorionic tumors have been established. They were numbered m-673, m-731 and m-786. At present they are transplanted over 25 generations and in this paper the morphology of both m-673 and m-731 was described. Biological behavior and morphological characteristics of paren...

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Veröffentlicht in:	The Tohoku Journal of Experimental Medicine 1973, Vol.111(2), pp.175-178
Hauptverfasser:	MIYAMOTO, MAKOTO, MATSUMOTO, KEISHI, SUGAYA, TORU
Format:	Artikel
Sprache:	eng
Schlagworte:	3β-ol-dehvdrogenase-isomerase svstem Animals Choriocarcinoma - enzymology Choriocarcinoma - pathology chorionic tumor Female Hydroxysteroid Dehydrogenases - analysis Isomerases - analysis Lung Neoplasms - pathology Male Multienzyme Complexes - analysis Neoplasm Metastasis Neoplasm Transplantation placenta Pregnancy Pregnenolone rat Rats transi lantation
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Zusammenfassung:	Three lines of transplantable chorionic tumors have been established. They were numbered m-673, m-731 and m-786. At present they are transplanted over 25 generations and in this paper the morphology of both m-673 and m-731 was described. Biological behavior and morphological characteristics of parent tumors resembled those of the human choriocarcinoma. Histological appearance of these two lines were similar to each other and with the advance of generations of transplantation, PAS positive substance in the cytoplasm gradually decreased. The specific enzyme, 3β-ol-dehydrogenase-isomerase system of normal rat placenta on this tumor (m-673) was detected.
ISSN:	0040-8727 1349-3329
DOI:	10.1620/tjem.111.175