Fluorescent Antibody Staining of Street and Fixed Rabies Virus Antigens

Fluorescent Antibody Staining of Street and Fixed Rabies Virus Antigens

Summary Methods of fixing and staining of rabies-infected mouse brain smears with fluorescent antibody are described. Evidence is presented that Negri bodies are of viral origin. The possible usefulness of this method for diagnosis of rabies in Negri negative animals and for serological determinatio...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1958-06, Vol.98 (2), p.219-223
Hauptverfasser: Goldwasser, R. A., Kissling, R. E.
Format: Artikel
Sprache:eng
Schlagworte:
Antigens, Viral
Fluorescent Antibody Technique
Immunoglobulins
Old Medline
Rabies - diagnosis
Rabies Vaccines
Rabies virus
Staining and Labeling
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Beschreibung
Zusammenfassung:Summary Methods of fixing and staining of rabies-infected mouse brain smears with fluorescent antibody are described. Evidence is presented that Negri bodies are of viral origin. The possible usefulness of this method for diagnosis of rabies in Negri negative animals and for serological determinations following immunization against rabies is indicated. Preliminary studies indicate that this technic may be useful in the detection of virus in salivary glands.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-98-23996