Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat
Summary Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a mark...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1958-05, Vol.98 (1), p.23-26 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Chappel, Clifford I. Rona, George Revesz, Clara Cahill, Joan |
description | Summary
Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a marked change in pituitary basophils. An increase in basophils of the pituitary has also been found in control rats with adrenal-regeneration hypertension. |
doi_str_mv | 10.3181/00379727-98-23927 |
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Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a marked change in pituitary basophils. An increase in basophils of the pituitary has also been found in control rats with adrenal-regeneration hypertension.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-98-23927</identifier><identifier>PMID: 13554529</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adrenal Gland Diseases ; Animals ; Hypertension ; Old Medline ; Propylthiouracil ; Rats ; Regeneration ; Thiouracil - analogs & derivatives</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1958-05, Vol.98 (1), p.23-26</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-32a56c0682372045826c273de9a3566bedb8413fc8b1ee057134593c9109ba113</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13554529$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chappel, Clifford I.</creatorcontrib><creatorcontrib>Rona, George</creatorcontrib><creatorcontrib>Revesz, Clara</creatorcontrib><creatorcontrib>Cahill, Joan</creatorcontrib><title>Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a marked change in pituitary basophils. An increase in basophils of the pituitary has also been found in control rats with adrenal-regeneration hypertension.</description><subject>Adrenal Gland Diseases</subject><subject>Animals</subject><subject>Hypertension</subject><subject>Old Medline</subject><subject>Propylthiouracil</subject><subject>Rats</subject><subject>Regeneration</subject><subject>Thiouracil - analogs & derivatives</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1958</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqXwA1hQJjYXf8SxPVYVUFAlUAWz5TiXNlWaFNsZ-u9JaBEb0-nunvcdHoRuKZlyqugDIVxqySTWCjOumTxDYyq4wDzT-hyNhz8egBG6CmFLCBWSZZdoRLkQqWB6jF4fyxJcTNoyefft_lDHTdV23rqqTtommRUeGlvjFayhAW9j1R8Xhz34CE0YlqpJ4gaSlY3X6KK0dYCb05ygz6fHj_kCL9-eX-azJXacq4g5syJzJFOMS0ZSoVjmmOQFaMtFluVQ5CqlvHQqpwBESMpTobnTlOjcUson6P7Yu_ftVwchml0VHNS1baDtglGMCtVr6EF6BJ1vQ_BQmr2vdtYfDCVmEGh-BRqtzI_APnN3Ku_yHRR_iZOxHpgegWDXYLa9q95P-KfxGzMmd54</recordid><startdate>195805</startdate><enddate>195805</enddate><creator>Chappel, Clifford I.</creator><creator>Rona, George</creator><creator>Revesz, Clara</creator><creator>Cahill, Joan</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195805</creationdate><title>Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat</title><author>Chappel, Clifford I. ; Rona, George ; Revesz, Clara ; Cahill, Joan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-32a56c0682372045826c273de9a3566bedb8413fc8b1ee057134593c9109ba113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1958</creationdate><topic>Adrenal Gland Diseases</topic><topic>Animals</topic><topic>Hypertension</topic><topic>Old Medline</topic><topic>Propylthiouracil</topic><topic>Rats</topic><topic>Regeneration</topic><topic>Thiouracil - analogs & derivatives</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chappel, Clifford I.</creatorcontrib><creatorcontrib>Rona, George</creatorcontrib><creatorcontrib>Revesz, Clara</creatorcontrib><creatorcontrib>Cahill, Joan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chappel, Clifford I.</au><au>Rona, George</au><au>Revesz, Clara</au><au>Cahill, Joan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1958-05</date><risdate>1958</risdate><volume>98</volume><issue>1</issue><spage>23</spage><epage>26</epage><pages>23-26</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a marked change in pituitary basophils. An increase in basophils of the pituitary has also been found in control rats with adrenal-regeneration hypertension.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13554529</pmid><doi>10.3181/00379727-98-23927</doi><tpages>4</tpages></addata></record> |
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subjects | Adrenal Gland Diseases Animals Hypertension Old Medline Propylthiouracil Rats Regeneration Thiouracil - analogs & derivatives |
title | Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat |
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