Effect of Propylthiouracil on Adrenal-Regeneration Hypertension in the Rat

Summary Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a mark...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1958-05, Vol.98 (1), p.23-26
Hauptverfasser: Chappel, Clifford I., Rona, George, Revesz, Clara, Cahill, Joan
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary Treatment of rats having adrenal-regeneration hypertension with propylthiouracil, results in decrease in body and tissue weights and marked lowering of hypertensive blood levels. This treatment also results in shrinking of width of the fasciculata zone in regenerated adrenal gland and a marked change in pituitary basophils. An increase in basophils of the pituitary has also been found in control rats with adrenal-regeneration hypertension.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-98-23927