Treatment of hypercholesterolemia with nicotinic acid

Treatment of hypercholesterolemia with nicotinic acid

Nicotinic acid was administered orally to 33 patients with hypercholesterolemia in doses varying from 1.5 to 6.0 Gm. per day for periods of 3 months to 1½ years. Significant, sustained, and reproducible decreases in the concentration of cholesterol and total lipids in the plasma and of serum beta-li...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 1958-04, Vol.17 (4, Part 1), p.497-504
Hauptverfasser: ACHOR, R W, BERGE, K G, BARKER, N W, McKENZIE, B F
Format: Artikel
Sprache:eng
Schlagworte:
Cholesterol - blood
Humans
Hypercholesterolemia
Niacin - therapeutic use
Nicotinic Acids
Old Medline
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Zusammenfassung:Nicotinic acid was administered orally to 33 patients with hypercholesterolemia in doses varying from 1.5 to 6.0 Gm. per day for periods of 3 months to 1½ years. Significant, sustained, and reproducible decreases in the concentration of cholesterol and total lipids in the plasma and of serum beta-lipoprotein cholesterol were observed in a majority of patients. This form of therapy appears to be effective, practical, and probably free from serious harmful effects.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.cir.17.4.497