Effect of Glucose Infusion on Adrenaline and Noradrenaline Secretion from the Adrenal Gland in Conscious Dogs

Conscious dogs were infused intravenously with glucose solution over 10 minutes. The samples of the adrenal venous blood were collected before and after the infusion of glucose and analyzed differentially for adrenaline and noradrenaline by the use of fluorimetric method. The blood glucose level was elevated by glucose infusion from 69-92mg/100 ml to 270-338mg/100 ml and then subsided gradually to the pre-infusion level. However, no definite changes in adrenaline and noradrenaline secretion were observed after the infusion of glucose.