Competition between collateral vessels

Competition between collateral vessels

The number of collateral vessels that supplies a given vascular bed tends to decrease. We suggest that this results from effects of the hydrodynamic drag of the stream on the endothelium. A mathematical model forms the basis for the argument. Some implications of this thesis on the natural history o...

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Veröffentlicht in:Cardiovascular research 1973-09, Vol.7 (5), p.670-675
Hauptverfasser: KEENAN, ROBERT L., RODBARD, SIMON
Format: Artikel
Sprache:eng
Schlagworte:
Arterial Occlusive Diseases - etiology
Blood Flow Velocity
Blood Pressure
Blood Viscosity
Collateral Circulation
Models, Biological
Rheology
Stress, Mechanical
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Zusammenfassung:The number of collateral vessels that supplies a given vascular bed tends to decrease. We suggest that this results from effects of the hydrodynamic drag of the stream on the endothelium. A mathematical model forms the basis for the argument. Some implications of this thesis on the natural history of clinical arterial stenoses are discussed.
ISSN:0008-6363
1755-3245
DOI:10.1093/cvr/7.5.670