Efficacy of Novastat against twelve strains of Eimeria tenella and the development of a Novastat-resistant strain

Novastat was efficacious against Eimeria tenella infections initiated by 7 of 12 drug-resistant strains and by a strain not previously exposed to drugs. The latter developed a tolerance to Novastat when propagated serially through chickens initially fed mash containing suboptimal levels of the cocci...

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Veröffentlicht in:	Avian diseases 1973-07, Vol.17 (3), p.582-585
Hauptverfasser:	McLoughlin, D.K, Chute, M.B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiprotozoal Agents - pharmacology Antiprotozoal Agents - therapeutic use Benzamides - pharmacology Benzamides - therapeutic use Chickens Coccidiosis - veterinary Coccidiostats Cross resistance Drug Combinations Drug Resistance, Microbial Eimeria - drug effects Experimentation Infections Lesions Oocysts Sulfonamides - pharmacology Sulfonamides - therapeutic use
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Beschreibung
Zusammenfassung:	Novastat was efficacious against Eimeria tenella infections initiated by 7 of 12 drug-resistant strains and by a strain not previously exposed to drugs. The latter developed a tolerance to Novastat when propagated serially through chickens initially fed mash containing suboptimal levels of the coccidiostat. The Novastat-resistant strain was cross-resistant to 5 of 15 other coccidiostats tested against it.
ISSN:	0005-2086 1938-4351
DOI:	10.2307/1589157