Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor
A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection.
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1973-09, Vol.62 (9), p.1464-1468 |
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| container_end_page | 1468 |
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| container_issue | 9 |
| container_start_page | 1464 |
| container_title | Journal of pharmaceutical sciences |
| container_volume | 62 |
| creator | Norton, Ted R. Kashiwagi, Midori Quinn, Ronald J. |
| description | A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection. |
| doi_str_mv | 10.1002/jps.2600620915 |
| format | Article |
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It is effective by either intraperitoneal or subcutaneous injection.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600620915</identifier><identifier>PMID: 4743093</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Animals ; Annelida ; Annelids ; Annelids, extract of Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice ; Antineoplastic Agents - administration & dosage ; Antineoplastic Agents - isolation & purification ; antitumor activity against Ehrlich ascites tumor in mice ; Antitumor activity-fraction isolated from annelid Reteterebella queenslandia ; Carcinoma, Ehrlich Tumor - drug therapy ; Chemical Phenomena ; Chemistry, Physical ; Chromatography ; Chromatography, Ion Exchange ; extract of Reteterebella queenslandia-isolation ; Gel permeation chromatography-isolation of extract from Reteterebella queenslandia ; Hydrolysis ; Leukemia, Experimental - drug therapy ; Mice ; Reteterebella queenslandia- isolation, antitumor activity against Ehrlich ascitcs tumor in mice ; Reteterebella queenslandia-isolation ; Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice ; Tissue Extracts - administration & dosage ; Tissue Extracts - therapeutic use</subject><ispartof>Journal of pharmaceutical sciences, 1973-09, Vol.62 (9), p.1464-1468</ispartof><rights>1973 Wiley‐Liss, Inc., A Wiley Company</rights><rights>Copyright © 1973 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3825-2f2260850e2e7b2102276f14d6e3399f9597c648902e248d2676adaade6d48093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600620915$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600620915$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4743093$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Norton, Ted R.</creatorcontrib><creatorcontrib>Kashiwagi, Midori</creatorcontrib><creatorcontrib>Quinn, Ronald J.</creatorcontrib><title>Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection.</description><subject>Animals</subject><subject>Annelida</subject><subject>Annelids</subject><subject>Annelids, extract of Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice</subject><subject>Antineoplastic Agents - administration & dosage</subject><subject>Antineoplastic Agents - isolation & purification</subject><subject>antitumor activity against Ehrlich ascites tumor in mice</subject><subject>Antitumor activity-fraction isolated from annelid Reteterebella queenslandia</subject><subject>Carcinoma, Ehrlich Tumor - drug therapy</subject><subject>Chemical Phenomena</subject><subject>Chemistry, Physical</subject><subject>Chromatography</subject><subject>Chromatography, Ion Exchange</subject><subject>extract of Reteterebella queenslandia-isolation</subject><subject>Gel permeation chromatography-isolation of extract from Reteterebella queenslandia</subject><subject>Hydrolysis</subject><subject>Leukemia, Experimental - drug therapy</subject><subject>Mice</subject><subject>Reteterebella queenslandia- isolation, antitumor activity against Ehrlich ascitcs tumor in mice</subject><subject>Reteterebella queenslandia-isolation</subject><subject>Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice</subject><subject>Tissue Extracts - administration & dosage</subject><subject>Tissue Extracts - therapeutic use</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAURS1EBQNl2x2SV6iVyNRxYideRiNKKdMvStWl5bFfOqZOMrUdKP--RhlRdYGQF168867ePQi9ysk8J4S-vdmEOeWEcEpEznbQLGeUZJzk1S6aJYBmBSvFPjoI4YYkjDC2h_bKqiyIKGaovQiDUxFw64cOxzXgpu_BWXOKryCm52EFzin8ewTog1O9sQq_bsYQvXJWvTnFjY72FrD6qWwfIj5be2f1GjdB2wgBX4_d4F-iF61yAY62_yH6_u7sevE-W34-v1g0y0wXNWUZbWnqUjMCFKoVzdP5FW_z0nAoCiFawUSleVkLQoGWtaG84sooZYCbsk6FDtHJlLvxQ7o4RNnZoB8K9DCMQdaUFIwJmsD5BGo_hOChlRtvO-XvZU7kg1iZxMp_YtPC8TZ5XHVgHvGtyTQX0_zOOrh_Jk1--PLtv-xs2rUhwp_HXeV_SV4VFZM_Pp3LS7JYfr26JPJj4uuJh6Ty1oKXyTX0Goz1oKM0g32qxl_216VQ</recordid><startdate>197309</startdate><enddate>197309</enddate><creator>Norton, Ted R.</creator><creator>Kashiwagi, Midori</creator><creator>Quinn, Ronald J.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197309</creationdate><title>Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor</title><author>Norton, Ted R. ; Kashiwagi, Midori ; Quinn, Ronald J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3825-2f2260850e2e7b2102276f14d6e3399f9597c648902e248d2676adaade6d48093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Animals</topic><topic>Annelida</topic><topic>Annelids</topic><topic>Annelids, extract of Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice</topic><topic>Antineoplastic Agents - administration & dosage</topic><topic>Antineoplastic Agents - isolation & purification</topic><topic>antitumor activity against Ehrlich ascites tumor in mice</topic><topic>Antitumor activity-fraction isolated from annelid Reteterebella queenslandia</topic><topic>Carcinoma, Ehrlich Tumor - drug therapy</topic><topic>Chemical Phenomena</topic><topic>Chemistry, Physical</topic><topic>Chromatography</topic><topic>Chromatography, Ion Exchange</topic><topic>extract of Reteterebella queenslandia-isolation</topic><topic>Gel permeation chromatography-isolation of extract from Reteterebella queenslandia</topic><topic>Hydrolysis</topic><topic>Leukemia, Experimental - drug therapy</topic><topic>Mice</topic><topic>Reteterebella queenslandia- isolation, antitumor activity against Ehrlich ascitcs tumor in mice</topic><topic>Reteterebella queenslandia-isolation</topic><topic>Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice</topic><topic>Tissue Extracts - administration & dosage</topic><topic>Tissue Extracts - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Norton, Ted R.</creatorcontrib><creatorcontrib>Kashiwagi, Midori</creatorcontrib><creatorcontrib>Quinn, Ronald J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Norton, Ted R.</au><au>Kashiwagi, Midori</au><au>Quinn, Ronald J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1973-09</date><risdate>1973</risdate><volume>62</volume><issue>9</issue><spage>1464</spage><epage>1468</epage><pages>1464-1468</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>4743093</pmid><doi>10.1002/jps.2600620915</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1973-09, Vol.62 (9), p.1464-1468 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82035592 |
| source | Wiley Online Library - AutoHoldings Journals; MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Annelida Annelids Annelids, extract of Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice Antineoplastic Agents - administration & dosage Antineoplastic Agents - isolation & purification antitumor activity against Ehrlich ascites tumor in mice Antitumor activity-fraction isolated from annelid Reteterebella queenslandia Carcinoma, Ehrlich Tumor - drug therapy Chemical Phenomena Chemistry, Physical Chromatography Chromatography, Ion Exchange extract of Reteterebella queenslandia-isolation Gel permeation chromatography-isolation of extract from Reteterebella queenslandia Hydrolysis Leukemia, Experimental - drug therapy Mice Reteterebella queenslandia- isolation, antitumor activity against Ehrlich ascitcs tumor in mice Reteterebella queenslandia-isolation Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice Tissue Extracts - administration & dosage Tissue Extracts - therapeutic use |
| title | Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor |
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