Isolate from the Annelid, Reteterebella queenslandia (Australia), Active against Ehrlich Ascites Tumor

A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1973-09, Vol.62 (9), p.1464-1468
Hauptverfasser:	Norton, Ted R., Kashiwagi, Midori, Quinn, Ronald J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annelida Annelids Annelids, extract of Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice Antineoplastic Agents - administration & dosage Antineoplastic Agents - isolation & purification antitumor activity against Ehrlich ascites tumor in mice Antitumor activity-fraction isolated from annelid Reteterebella queenslandia Carcinoma, Ehrlich Tumor - drug therapy Chemical Phenomena Chemistry, Physical Chromatography Chromatography, Ion Exchange extract of Reteterebella queenslandia-isolation Gel permeation chromatography-isolation of extract from Reteterebella queenslandia Hydrolysis Leukemia, Experimental - drug therapy Mice Reteterebella queenslandia- isolation, antitumor activity against Ehrlich ascitcs tumor in mice Reteterebella queenslandia-isolation Reteterebella queenslandia—isolation, antitumor activity against Ehrlich ascites tumor in mice Tissue Extracts - administration & dosage Tissue Extracts - therapeutic use
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Beschreibung
Zusammenfassung:	A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600620915