The Local Response of Tissue Mast Cells to Antigen in Sensitized Mice

It was observed that locally injected antigen initiates a more wide-spread degranulation of local tissue mast cells in sensitized mice than in controls. The fate of the shed mast celt granules in the tissues is described and the significance of various aspects of mast cell degranulation is discussed...

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Veröffentlicht in:	The Journal of immunology (1950) 1957-09, Vol.79 (3), p.259-264
Hauptverfasser:	Carter, Paul B, Higginbotham, R. D, Dougherty, Thomas F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Hypersensitivity Immune System Diseases Mast Cells Mice Old Medline
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	It was observed that locally injected antigen initiates a more wide-spread degranulation of local tissue mast cells in sensitized mice than in controls. The fate of the shed mast celt granules in the tissues is described and the significance of various aspects of mast cell degranulation is discussed.
ISSN:	0022-1767 1550-6606
DOI:	10.4049/jimmunol.79.3.259