Response of Oral Tissues to Grafts of Ethylenediamine-treated Heterogeneous Bone

PREVIOUS work has shown that ‘anorganic’ (ethylenediamine-extracted) bone can serve as a successful foundation for new osseous growth in long-bone defects of the dog 1−3 . The objective of this present study using nine rhesus ( Macaca mulatta ) monkeys was to determine if the response of the oral tissues to osseous ‘anorganic’ heterografts was similar to that of the host tissue of the long bones. Eleven mandibular and five maxillary heterogeneous grafts were inserted into two types of osseous defects: ( a ) an ‘exodontic’ or alveolectomy defect produced by the extraction of the permanent molar and bicuspid teeth; ( b ) a deep ‘cystic’ type of bone cavity produced by the removal of unerupted molar and cuspid teeth.