Suppression of feeding in cats following 2-deoxy-D-glucose

Suppression of feeding in cats following 2-deoxy-D-glucose

The glucose utilization hypothesis for the control of food intake postulates that decreases in cellular glucose metabolism initiate feeding. In contrast to findings reported with other species, inhibition of glycolysis with 2-deoxy-D-glucose does not increase feeding in cats, but produces dose-depen...

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Veröffentlicht in:Physiology & behavior 1973-04, Vol.10 (4), p.805-807
Hauptverfasser: Jalowiec, John E., Panksepp, Jaak, Shabshelowitz, Harlan, Zolovick, Andrew J., Stern, Warren, Morgane, Peter J.
Format: Artikel
Sprache:eng
Schlagworte:
2-deoxy-D-glucose
Animals
Cats
Dose-Response Relationship, Drug
Eating - drug effects
Feeding
Feeding Behavior - drug effects
Female
Glucose - administration & dosage
Glucose - metabolism
Glucose - pharmacology
Glycolysis - drug effects
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Beschreibung
Zusammenfassung:The glucose utilization hypothesis for the control of food intake postulates that decreases in cellular glucose metabolism initiate feeding. In contrast to findings reported with other species, inhibition of glycolysis with 2-deoxy-D-glucose does not increase feeding in cats, but produces dose-dependent decreases in food intake. Accordingly, glucostatic control of feeding may be qualitatively different in cats than in other species.
ISSN:0031-9384
1873-507X
DOI:10.1016/0031-9384(73)90166-2