Isolation and In Vitro Antifungal Activity of 6,6'-Dihydroxythiobinupharidine

The isolation procedure for obtaining a new nuphar alkaloid, 6,6'-dihydroxythiobinupharidine (formerly named 6,6'- dihydroxythionuphlutine-A), and its in vitro activity against eight human pathogenic fungi are described.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1973-05, Vol.62 (5), p.826-827
Hauptverfasser:	Cullen, W.P., LaLonpe, R.T., Wang, C.J., Wong, C.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	6,6'-Dihydroxythiobinupharidine—isolation from Nuphar luteum subsp. macrophyllum, tested for antifungal activity 6′-dihydroxythiobinupharidine 6′-dihydroxythiobinupharidine from Nuphar luteum subsp. macrophyllum 6′-Dihydroxythiobinupharidine-isolation from Nuphar luteum subsp. macrophyllum Alkaloids - administration & dosage Alkaloids - isolation & purification Alkaloids - pharmacology Antifungal agents Antifungal Agents - administration & dosage Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Antifungal agents, potential—isolation and testing of 6,6'-dihydroxythiobinupharidine from Nuphar luteum subsp. macrophyllum Blastomyces - drug effects Candida albicans - drug effects Cryptococcus neoformans - drug effects Histoplasma - drug effects Microsporum - drug effects Nuphar luteum subsp. macrophyllum (Beal)-isolation of 6 Nuphar luteum subsp. macrophyllum (Beal)—isolation of 6,6'-dihydroxythiobinupharidine, tested for antifungal activity Plants, Medicinal potential-isolation and testing of 6 tested for antifungal activity Trichophyton - drug effects
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Beschreibung
Zusammenfassung:	The isolation procedure for obtaining a new nuphar alkaloid, 6,6'-dihydroxythiobinupharidine (formerly named 6,6'- dihydroxythionuphlutine-A), and its in vitro activity against eight human pathogenic fungi are described.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600620530