Fluoroarterenol: a Fluorine Isostere of Norepinephrine

IN an investigation of the enzymatic methylation of norepinephrine, certain of the isosteres of this neurohormone, designed as antagonists of this system, have been synthesized. This communication deals with D , L -3,4-dihydroxy-(α-fluoromethyl)benzylalcohol, fluoroarterenol, its synthesis and biolo...

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Veröffentlicht in:Nature (London) 1957-02, Vol.179 (4553), p.265-266
1. Verfasser: FELLMAN, J. H
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description IN an investigation of the enzymatic methylation of norepinephrine, certain of the isosteres of this neurohormone, designed as antagonists of this system, have been synthesized. This communication deals with D , L -3,4-dihydroxy-(α-fluoromethyl)benzylalcohol, fluoroarterenol, its synthesis and biological properties.
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source MEDLINE; Nature; SpringerNature Journals
subjects Fluorides
Fluorine
Humanities and Social Sciences
letter
multidisciplinary
Norepinephrine - analogs & derivatives
Old Medline
Science
Science (multidisciplinary)
title Fluoroarterenol: a Fluorine Isostere of Norepinephrine
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