Influence of Analgesic Amines on Plasma Cholesterol of Rats

ANALGESIC amines may influence, or be influenced by, the level of thyroid activity, for example, hypothyroid rats compared to normal controls gave enhanced response to 1-( p - cyclo hexyloxyphenyl)ethylamine in analgesic assay. While seeking the chemical basis for morphine-like activity, by comparison of the above amine with its inactive analogue, 1-( p - iso propyloxyphenyl)ethylamine 1 , the possibility was considered whether analgesic amines might interfere in processes that are linked to thyroxine.