Primary cutaneous anaplastic large-cell lymphoma

Primary cutaneous anaplastic large-cell lymphoma (ALCL) is a form of cutaneous T-cell lymphoma that is characterized by solitary or localized nodules or plaques. Histopathologic features include a diffuse, non-epidermotropic infiltrate with cohesive sheets of large anaplastic CD30+ tumor cells. This...

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Veröffentlicht in:	Dermatology online journal 2010-11, Vol.16 (11), p.2-2
Hauptverfasser:	Newlove, Tracey, Loyd, Aaron, Patel, Rishi, Jelinek, Josef, Latkowski, Jo-Ann
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged, 80 and over Combined Modality Therapy Humans Ki-1 Antigen - metabolism Lymphoma, Primary Cutaneous Anaplastic Large Cell - diagnosis Lymphoma, Primary Cutaneous Anaplastic Large Cell - pathology Lymphoma, Primary Cutaneous Anaplastic Large Cell - radiotherapy Lymphoma, Primary Cutaneous Anaplastic Large Cell - surgery Male Skin Neoplasms - diagnosis Skin Neoplasms - pathology Skin Neoplasms - radiotherapy Skin Neoplasms - surgery Treatment Outcome
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Beschreibung
Zusammenfassung:	Primary cutaneous anaplastic large-cell lymphoma (ALCL) is a form of cutaneous T-cell lymphoma that is characterized by solitary or localized nodules or plaques. Histopathologic features include a diffuse, non-epidermotropic infiltrate with cohesive sheets of large anaplastic CD30+ tumor cells. This entity must be distinguished from systemic ALCL with cutaneous involvement and lymphomatoid papulosis. Treatment modalities include clinical monitoring, radiation therapy, and surgical excision, with systemic chemotherapy reserved for disseminated or extracutaneous disease.
ISSN:	1087-2108 1087-2108
DOI:	10.5070/D34N62V82W