Activity of Platelet Hemostasis in Children with Spinal Deformities

An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand's factor in the vascular wall and intensification of thromboxane production in blood platele...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2010-10, Vol.149 (5), p.645-646
Hauptverfasser: Medvedev, I. N, Lapshina, E. V, Zavalishina, S. Yu
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container_title Bulletin of experimental biology and medicine
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creator Medvedev, I. N
Lapshina, E. V
Zavalishina, S. Yu
description An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand's factor in the vascular wall and intensification of thromboxane production in blood platelets. Activation of thromboxane formation is the main cause of platelet hyperactivity in children with scoliosis. Correction of platelet hemostasis may include pathogenetically substantiated complex of therapeutic exercises, swimming, and massage.
doi_str_mv 10.1007/s10517-010-1014-0
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subjects Attention-deficit hyperactivity disorder
Biomedical and Life Sciences
Biomedicine
Blood Platelets - physiology
Cell Biology
Child
Child, Preschool
Children
Exercise therapy
Exercise therapy for children
Female
Hemostasis - physiology
Humans
Internal Medicine
Laboratory Medicine
Male
Pathology
Physiological aspects
platelets
Scoliosis
Scoliosis - blood
Thromboxanes - biosynthesis
von Willebrand Factor - biosynthesis
title Activity of Platelet Hemostasis in Children with Spinal Deformities
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