Activity of Platelet Hemostasis in Children with Spinal Deformities

An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand's factor in the vascular wall and intensification of thromboxane production in blood platele...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2010-10, Vol.149 (5), p.645-646
Hauptverfasser:	Medvedev, I. N, Lapshina, E. V, Zavalishina, S. Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention-deficit hyperactivity disorder Biomedical and Life Sciences Biomedicine Blood Platelets - physiology Cell Biology Child Child, Preschool Children Exercise therapy Exercise therapy for children Female Hemostasis - physiology Humans Internal Medicine Laboratory Medicine Male Pathology Physiological aspects platelets Scoliosis Scoliosis - blood Thromboxanes - biosynthesis von Willebrand Factor - biosynthesis
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Beschreibung
Zusammenfassung:	An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand's factor in the vascular wall and intensification of thromboxane production in blood platelets. Activation of thromboxane formation is the main cause of platelet hyperactivity in children with scoliosis. Correction of platelet hemostasis may include pathogenetically substantiated complex of therapeutic exercises, swimming, and massage.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-010-1014-0