Effect of estrogens on the uterine blood flow of oophorectomized ewes

Quantitative information about dilatation of uterine blood vessels after administration of estrogens is needed, e.g., the dose response of uterine blood flow to estrogens, whether different estrogens are equipotent in inducing vasodilation, the maximum obtainable blood flow to the nonpregnant uterus under maximum estrogen stimulation, and the related chain of biochemical events. The type of biological preparation developed and the results obtained thus far form the substance of this report.