Facile Preparation of a Hybrid Nanoprobe for Triple-Modality Optical/PET/MR Imaging
A facile method of preparing triple‐modality, optical–nuclear–magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optica...
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| Veröffentlicht in: | Small (Weinheim an der Bergstrasse, Germany) Germany), 2010-12, Vol.6 (24), p.2863-2868 |
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| container_issue | 24 |
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| container_title | Small (Weinheim an der Bergstrasse, Germany) |
| container_volume | 6 |
| creator | Park, Jeong Chan Yu, Mi Kyung An, Gwang Il Park, Se-Il Oh, Jungmin Kim, Hong Joo Kim, Joo-Hyun Wang, Eun Kyung Hong, Il-Hwa Ha, Yeong Su Choi, Tae Hyun Jeong, Kyu-Shik Chang, Yongmin Welch, Michael J. Jon, Sangyong Yoo, Jeongsoo |
| description | A facile method of preparing triple‐modality, optical–nuclear–magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non‐invasive differentiation between tumor‐metastasized sentinel lymph nodes (SLNs) and tumor‐free SLNs. |
| doi_str_mv | 10.1002/smll.201001418 |
| format | Article |
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Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non‐invasive differentiation between tumor‐metastasized sentinel lymph nodes (SLNs) and tumor‐free SLNs.</description><identifier>ISSN: 1613-6810</identifier><identifier>EISSN: 1613-6829</identifier><identifier>DOI: 10.1002/smll.201001418</identifier><identifier>PMID: 21104828</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Algorithms ; hybrid materials ; imaging agents ; Magnetic Resonance Imaging - methods ; multimodality imaging ; nanoparticles ; Nanotechnology - instrumentation ; Nanotechnology - methods ; Optical Devices ; Positron-Emission Tomography - methods</subject><ispartof>Small (Weinheim an der Bergstrasse, Germany), 2010-12, Vol.6 (24), p.2863-2868</ispartof><rights>Copyright © 2010 WILEY‐VCH Verlag GmbH & Co. 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Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non‐invasive differentiation between tumor‐metastasized sentinel lymph nodes (SLNs) and tumor‐free SLNs.</description><subject>Algorithms</subject><subject>hybrid materials</subject><subject>imaging agents</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>multimodality imaging</subject><subject>nanoparticles</subject><subject>Nanotechnology - instrumentation</subject><subject>Nanotechnology - methods</subject><subject>Optical Devices</subject><subject>Positron-Emission Tomography - methods</subject><issn>1613-6810</issn><issn>1613-6829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAUhS0E4r0yIm9Maf1MnBFVFJBSKBCExGLZiY0MThPsVNB_T1ChYmO6Z_jO0dUHwAlGI4wQGcfG-xFBQ8YMiy2wj1NMk1SQfHuTMdoDBzG-IkQxYdku2CMYIyaI2AcPU1U5b-A8mE4F1bt2AVsLFbxa6eBqeKMWbRdabaBtAyyD67xJZm2tvOtX8LbrXaX8eH5Rjmf38LpRL27xcgR2rPLRHP_cQ_A4vSgnV0lxe3k9OS-SijEhElZnGTG84jSnNs9IThm32BpU1zwlFhtiMy4YJlynhGpqK8V4rnWllWFEc3oIzta7w4PvSxN72bhYGe_VwrTLKAUWDBGO8oEcrckqtDEGY2UXXKPCSmIkvz3Kb49y43EonP5ML3Vj6g3-K24A8jXwMdhb_TMnH2ZF8Xc8WXdd7M3npqvCm0wzmnH5dHMpyzLLi8nznZzTL1iWjXg</recordid><startdate>20101220</startdate><enddate>20101220</enddate><creator>Park, Jeong Chan</creator><creator>Yu, Mi Kyung</creator><creator>An, Gwang Il</creator><creator>Park, Se-Il</creator><creator>Oh, Jungmin</creator><creator>Kim, Hong Joo</creator><creator>Kim, Joo-Hyun</creator><creator>Wang, Eun Kyung</creator><creator>Hong, Il-Hwa</creator><creator>Ha, Yeong Su</creator><creator>Choi, Tae Hyun</creator><creator>Jeong, Kyu-Shik</creator><creator>Chang, Yongmin</creator><creator>Welch, Michael J.</creator><creator>Jon, Sangyong</creator><creator>Yoo, Jeongsoo</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20101220</creationdate><title>Facile Preparation of a Hybrid Nanoprobe for Triple-Modality Optical/PET/MR Imaging</title><author>Park, Jeong Chan ; 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| subjects | Algorithms hybrid materials imaging agents Magnetic Resonance Imaging - methods multimodality imaging nanoparticles Nanotechnology - instrumentation Nanotechnology - methods Optical Devices Positron-Emission Tomography - methods |
| title | Facile Preparation of a Hybrid Nanoprobe for Triple-Modality Optical/PET/MR Imaging |
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