Thyroxine and succinate oxidation

Thyroxine and succinate oxidation

1. 1. Thyroxine preserves the activity of succinate-cytochrome c reductase activity in preparations from rat heart homogenate, but does not increase the original activity. 2. 2. The preservation appears to be a chemical rather than physical effect. 3. 3. At least one site of action is in the succini...

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Veröffentlicht in:Archives of biochemistry and biophysics 1956-02, Vol.60 (2), p.320-328
Hauptverfasser: Kripke, Benjamin J., Bever, Arley T.
Format: Artikel
Sprache:eng
Schlagworte:
Myocardium - metabolism
Old Medline
Oxidation-Reduction
Oxidoreductases - analysis
Succinates
Succinic Acid
Thyroxine - pharmacology
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Zusammenfassung:1. 1. Thyroxine preserves the activity of succinate-cytochrome c reductase activity in preparations from rat heart homogenate, but does not increase the original activity. 2. 2. The preservation appears to be a chemical rather than physical effect. 3. 3. At least one site of action is in the succinic dehydrogenase complex where sulfhydryl groups are protected from oxidation.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(56)90434-9