Selection of Best pH Range for Extraction of Amine-Bromthymol Blue Complexes

This paper describes the determination of the best pH range for the extraction of amine-bromthymol blue complexes with chloroform. The experimental data on eight amine salts indicate that the best pH range is about 5.2-6.4 for a greater sensitivity in the analytical technique. A theoretical equation...

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Veröffentlicht in:Journal of pharmaceutical sciences 1973-02, Vol.62 (2), p.311-313
Hauptverfasser: Das Gupta, V., Herman, Harvey B.
Format: Artikel
Sprache:eng
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Zusammenfassung:This paper describes the determination of the best pH range for the extraction of amine-bromthymol blue complexes with chloroform. The experimental data on eight amine salts indicate that the best pH range is about 5.2-6.4 for a greater sensitivity in the analytical technique. A theoretical equation was derived and solved using a computer. The experimental results are in fairly good agreement with the theoretical results.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600620228