Cyclic Fluctuation in Blood Granulocyte DNA Labeling: Comparison of Tritiated Thymidine and Radiophosphorus

Cyclic Fluctuation in Blood Granulocyte DNA Labeling: Comparison of Tritiated Thymidine and Radiophosphorus

DNA labeling studies with 3HT and 32P have been done in horses. Frequent sampling has defined cyclic fluctuations in blood granulocyte DNA label content with a cycle time of around 27 hr. Simultaneous labeling studies in the same animals have produced blood granulocyte DNA labeling curves that are n...

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Veröffentlicht in:Blood 1973-01, Vol.41 (1), p.123-130
Hauptverfasser: Walker, Richard I., Cole, Enser W., Glasser, Robert M., Herion, John C., Palmer, Jeffress G.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
DNA
Hematocrit
Horses
Isotope Labeling
Leukocyte Count
Leukocytes
Phosphorus Isotopes
Thymidine - metabolism
Tritium
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Zusammenfassung:DNA labeling studies with 3HT and 32P have been done in horses. Frequent sampling has defined cyclic fluctuations in blood granulocyte DNA label content with a cycle time of around 27 hr. Simultaneous labeling studies in the same animals have produced blood granulocyte DNA labeling curves that are nearly identical indicating significant reutilization of 3HT.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V41.1.123.123