A Simple Test for Erythropoietin in Deproteinized Plasma Extract.
Summary and Conclusions A simple test for erythropoietin in deproteinized plasma extract is described. A total of 3 or 4 days is required for subcutaneous injection of the plasma extract and only one intravenous injection of Fe59 is necessary. When concentrated plasma extracts are given to hypophy-s...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1956-12, Vol.93 (3), p.473-475 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Mirand, E. A. Prentice, T. C. |
description | Summary and Conclusions
A simple test for erythropoietin in deproteinized plasma extract is described. A total of 3 or 4 days is required for subcutaneous injection of the plasma extract and only one intravenous injection of Fe59 is necessary. When concentrated plasma extracts are given to hypophy-sectomized rats, 6 to 9 fold differences in response between anemic and control groups are achieved. The deproteinized nature of the material enables cross-species examination of the erythropoietic factor. |
doi_str_mv | 10.3181/00379727-93-22791 |
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A simple test for erythropoietin in deproteinized plasma extract is described. A total of 3 or 4 days is required for subcutaneous injection of the plasma extract and only one intravenous injection of Fe59 is necessary. When concentrated plasma extracts are given to hypophy-sectomized rats, 6 to 9 fold differences in response between anemic and control groups are achieved. The deproteinized nature of the material enables cross-species examination of the erythropoietic factor.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-93-22791</identifier><identifier>PMID: 13389494</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Epoetin Alfa ; Erythrocytes ; Erythropoietin ; Humans ; Old Medline ; Plasma ; Protein Binding</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1956-12, Vol.93 (3), p.473-475</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-35b43a6babe29005265f73cc5d0e286d6c9a43aa70b537037b1c48c2716331603</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13389494$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mirand, E. A.</creatorcontrib><creatorcontrib>Prentice, T. C.</creatorcontrib><title>A Simple Test for Erythropoietin in Deproteinized Plasma Extract.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary and Conclusions
A simple test for erythropoietin in deproteinized plasma extract is described. A total of 3 or 4 days is required for subcutaneous injection of the plasma extract and only one intravenous injection of Fe59 is necessary. When concentrated plasma extracts are given to hypophy-sectomized rats, 6 to 9 fold differences in response between anemic and control groups are achieved. The deproteinized nature of the material enables cross-species examination of the erythropoietic factor.</description><subject>Epoetin Alfa</subject><subject>Erythrocytes</subject><subject>Erythropoietin</subject><subject>Humans</subject><subject>Old Medline</subject><subject>Plasma</subject><subject>Protein Binding</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1956</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EoqXwAWxQVuxSbE9sx8uqhIdUCSTK2nIcB1LlhZ1IlK_HpUXskEaaxZy5c-cidEnwHEhKbjAGIQUVsYSYUiHJEZoSBiwGLuUxmu7m8Q6YoDPvNxgTJig_RRMCkMpEJlO0WEQvVdPXNlpbP0Rl56LMbYd31_VdZYeqjULd2t51g63a6ssW0XOtfaOj7HNw2gzzc3RS6trbi0Ofode7bL18iFdP94_LxSo24dgQA8sT0DzXuaUSY0Y5KwUYwwpsacoLbqQOgBY4ZyCC8ZyYJDVUEA5AOIYZut7rBi8fYzCrmsobW9e6td3oVUqEYEE3gGQPGtd572ypelc12m0VwWqXm_rNTUlQP7mFnauD-Jg3tvjbOAQVgPke8PrNqk03ujY8-4_iN-3ydCE</recordid><startdate>195612</startdate><enddate>195612</enddate><creator>Mirand, E. A.</creator><creator>Prentice, T. C.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195612</creationdate><title>A Simple Test for Erythropoietin in Deproteinized Plasma Extract.</title><author>Mirand, E. A. ; Prentice, T. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-35b43a6babe29005265f73cc5d0e286d6c9a43aa70b537037b1c48c2716331603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1956</creationdate><topic>Epoetin Alfa</topic><topic>Erythrocytes</topic><topic>Erythropoietin</topic><topic>Humans</topic><topic>Old Medline</topic><topic>Plasma</topic><topic>Protein Binding</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mirand, E. A.</creatorcontrib><creatorcontrib>Prentice, T. C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mirand, E. A.</au><au>Prentice, T. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Simple Test for Erythropoietin in Deproteinized Plasma Extract.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1956-12</date><risdate>1956</risdate><volume>93</volume><issue>3</issue><spage>473</spage><epage>475</epage><pages>473-475</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary and Conclusions
A simple test for erythropoietin in deproteinized plasma extract is described. A total of 3 or 4 days is required for subcutaneous injection of the plasma extract and only one intravenous injection of Fe59 is necessary. When concentrated plasma extracts are given to hypophy-sectomized rats, 6 to 9 fold differences in response between anemic and control groups are achieved. The deproteinized nature of the material enables cross-species examination of the erythropoietic factor.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13389494</pmid><doi>10.3181/00379727-93-22791</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Epoetin Alfa Erythrocytes Erythropoietin Humans Old Medline Plasma Protein Binding |
title | A Simple Test for Erythropoietin in Deproteinized Plasma Extract. |
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