Acute and chronic cardiovascular effects of pentolinium in hypertensive patients

Using a tracer injection technic, modified to provide accurate and repeated determinations of cardiac output in the ambulatory patient, the authors have shown that chronic pentolinium therapy for hypertension lowers blood pressure by reducing cardiac output in the seated position. From these observa...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1956-12, Vol.14 (6), p.1061-1068
Hauptverfasser:	HOOBLER, S W, SMITH, J R
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular Agents Cardiovascular System - drug effects Humans Hypertension - therapy Muscle Relaxants, Central - pharmacology Old Medline Pentolinium Tartrate
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description	Using a tracer injection technic, modified to provide accurate and repeated determinations of cardiac output in the ambulatory patient, the authors have shown that chronic pentolinium therapy for hypertension lowers blood pressure by reducing cardiac output in the seated position. From these observations and the work of others, they believe that the effect of ganglionic blockade on venoconstrictor tone deserves greater emphasis.
doi_str_mv	10.1161/01.CIR.14.6.1061
format	Article
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source	MEDLINE; American Heart Association Journals; EZB-FREE-00999 freely available EZB journals; Journals@Ovid Complete
subjects	Cardiovascular Agents Cardiovascular System - drug effects Humans Hypertension - therapy Muscle Relaxants, Central - pharmacology Old Medline Pentolinium Tartrate
title	Acute and chronic cardiovascular effects of pentolinium in hypertensive patients
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